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Summarize Variables

Source: R/summarize_variables.R
summarize_variables.Rd

[Stable]

We use the S3 generic function s_summary() to implement summaries for different x objects. This is used as a statistics function in combination with the analyze function summarize_vars().

Usage 

s_summary(x, na.rm = TRUE, denom, .N_row, .N_col, .var, ...)

# S3 method for numeric
s_summary(
  x,
  na.rm = TRUE,
  denom,
  .N_row,
  .N_col,
  .var,
  control = control_summarize_vars(),
  ...
)

# S3 method for factor
s_summary(
  x,
  na.rm = TRUE,
  denom = c("n", "N_row", "N_col"),
  .N_row,
  .N_col,
  ...
)

# S3 method for character
s_summary(
  x,
  na.rm = TRUE,
  denom = c("n", "N_row", "N_col"),
  .N_row,
  .N_col,
  .var,
  verbose = TRUE,
  ...
)

# S3 method for logical
s_summary(
  x,
  na.rm = TRUE,
  denom = c("n", "N_row", "N_col"),
  .N_row,
  .N_col,
  ...
)

a_summary(x, ..., .N_row, .N_col, .var)

# S3 method for numeric
a_summary(
  x,
  na.rm = TRUE,
  denom,
  .N_row,
  .N_col,
  .var,
  control = control_summarize_vars(),
  ...
)

# S3 method for factor
a_summary(
  x,
  na.rm = TRUE,
  denom = c("n", "N_row", "N_col"),
  .N_row,
  .N_col,
  ...
)

# S3 method for character
a_summary(
  x,
  na.rm = TRUE,
  denom = c("n", "N_row", "N_col"),
  .N_row,
  .N_col,
  .var,
  verbose = TRUE,
  ...
)

# S3 method for logical
a_summary(
  x,
  na.rm = TRUE,
  denom = c("n", "N_row", "N_col"),
  .N_row,
  .N_col,
  ...
)

summarize_vars(
  lyt,
  vars,
  var_labels = vars,
  nested = TRUE,
  ...,
  na_level = NA_character_,
  show_labels = "default",
  table_names = vars,
  section_div = NA_character_,
  .stats = c("n", "mean_sd", "median", "range", "count_fraction"),
  .formats = NULL,
  .labels = NULL,
  .indent_mods = NULL
)

Arguments

x

(numeric)
vector of numbers we want to analyze.

na.rm

(flag)
whether NA values should be removed from x prior to analysis.

denom

(string)
choice of denominator for proportion. Options are:

  • n: number of values in this row and column intersection.

  • N_row: total number of values in this row across columns.

  • N_col: total number of values in this column across rows.

.N_row

(count)
column-wise N (column count) for the full column that is passed by rtables.

.N_col

(count)
row-wise N (row group count) for the group of observations being analyzed (i.e. with no column-based subsetting) that is passed by rtables.

.var

(string)
single variable name that is passed by rtables when requested by a statistics function.

...

arguments passed to s_summary().

control

(list)
parameters for descriptive statistics details, specified by using the helper function control_summarize_vars(). Some possible parameter options are:

  • conf_level (proportion)
    confidence level of the interval for mean and median.

  • quantiles (numeric)
    vector of length two to specify the quantiles.

  • quantile_type (numeric)
    between 1 and 9 selecting quantile algorithms to be used. See more about type in stats::quantile().

  • test_mean (numeric)
    value to test against the mean under the null hypothesis when calculating p-value.

verbose

(logical)
Defaults to TRUE, which prints out warnings and messages. It is mainly used to print out information about factor casting.

lyt

(layout)
input layout where analyses will be added to.

vars

(character)
variable names for the primary analysis variable to be iterated over.

var_labels

(character)
character for label.

nested

(flag)
whether this layout instruction be applied within the existing layout structure if possible (TRUE, the default) or as a new top-level element (FALSE). Ignored if it would nest a split underneath analyses, which is not allowed.

na_level

(string)
string used to replace all NA or empty values in the output.

show_labels

(string)
label visibility: one of "default", "visible" and "hidden".

table_names

(character)
this can be customized in case that the same vars are analyzed multiple times, to avoid warnings from rtables.

section_div

(string)
string which should be repeated as a section divider after each group defined by this split instruction, or NA_character_ (the default) for no section divider.

.stats

(character)
statistics to select for the table.

.formats

(named character or list)
formats for the statistics.

.labels

(named character)
labels for the statistics (without indent).

.indent_mods

(named vector of integer)
indent modifiers for the labels. Each element of the vector should be a name-value pair with name corresponding to a statistic specified in .stats and value the indentation for that statistic's row label.

Value

  • s_summary() returns different statistics depending on the class of x.

  • If x is of class factor or converted from character, returns a list with named numeric items:

    • n: The length() of x.

    • count: A list with the number of cases for each level of the factor x.

    • count_fraction: Similar to count but also includes the proportion of cases for each level of the factor x relative to the denominator, or NA if the denominator is zero.

  • If x is of class logical, returns a list with named numeric items:

    • n: The length() of x (possibly after removing NAs).

    • count: Count of TRUE in x.

    • count_fraction: Count and proportion of TRUE in x relative to the denominator, or NA if the denominator is zero. Note that NAs in x are never counted or leading to NA here.

  • summarize_vars() returns a layout object suitable for passing to further layouting functions, or to rtables::build_table(). Adding this function to an rtable layout will add formatted rows containing the statistics from s_summary() to the table layout.

Functions

  • s_summary(): S3 generic function to produces a variable summary.

  • s_summary(numeric): Method for numeric class.

  • s_summary(factor): Method for factor class.

  • s_summary(character): Method for character class. This makes an automatic conversion to factor (with a warning) and then forwards to the method for factors.

  • s_summary(logical): Method for logical class.

  • a_summary(): Formatted analysis function which is used as afun in summarize_vars().

  • a_summary(numeric): Formatted analysis function method for numeric class.

  • a_summary(factor): Formatted analysis function method for factor class.

  • a_summary(character): Formatted analysis function method for character class.

  • a_summary(logical): Formatted analysis function method for logical class.

  • summarize_vars(): Layout-creating function which can take statistics function arguments and additional format arguments. This function is a wrapper for rtables::analyze().

Note

  • If x is an empty vector, NA is returned. This is the expected feature so as to return rcell content in rtables when the intersection of a column and a row delimits an empty data selection.

  • When the mean function is applied to an empty vector, NA will be returned instead of NaN, the latter being standard behavior in R.

  • If x is an empty factor, a list is still returned for counts with one element per factor level. If there are no levels in x, the function fails.

  • If factor variables contain NA, these NA values are excluded by default. To include NA values set na.rm = FALSE and missing values will be displayed as an NA level. Alternatively, an explicit factor level can be defined for NA values during pre-processing via df_explicit_na() - the default na_level ("<Missing>") will also be excluded when na.rm is set to TRUE.

  • Automatic conversion of character to factor does not guarantee that the table can be generated correctly. In particular for sparse tables this very likely can fail. It is therefore better to always pre-process the dataset such that factors are manually created from character variables before passing the dataset to rtables::build_table().

Examples 

# `s_summary.numeric`

## Basic usage: empty numeric returns NA-filled items.
s_summary(numeric())
#> $n
#> n 
#> 0 
#> 
#> $sum
#> sum 
#>  NA 
#> 
#> $mean
#> mean 
#>   NA 
#> 
#> $sd
#> sd 
#> NA 
#> 
#> $se
#> se 
#> NA 
#> 
#> $mean_sd
#> mean   sd 
#>   NA   NA 
#> 
#> $mean_se
#> mean   se 
#>   NA   NA 
#> 
#> $mean_ci
#> mean_ci_lwr mean_ci_upr 
#>          NA          NA 
#> attr(,"label")
#> [1] "Mean 95% CI"
#> 
#> $mean_sei
#> mean_sei_lwr mean_sei_upr 
#>           NA           NA 
#> attr(,"label")
#> [1] "Mean -/+ 1xSE"
#> 
#> $mean_sdi
#> mean_sdi_lwr mean_sdi_upr 
#>           NA           NA 
#> attr(,"label")
#> [1] "Mean -/+ 1xSD"
#> 
#> $mean_pval
#> p_value 
#>      NA 
#> attr(,"label")
#> [1] "Mean p-value (H0: mean = 0)"
#> 
#> $median
#> median 
#>     NA 
#> 
#> $mad
#> mad 
#>  NA 
#> 
#> $median_ci
#> median_ci_lwr median_ci_upr 
#>            NA            NA 
#> attr(,"conf_level")
#> [1] NA
#> attr(,"label")
#> [1] "Median 95% CI"
#> 
#> $quantiles
#> quantile_0.25 quantile_0.75 
#>            NA            NA 
#> attr(,"label")
#> [1] "25% and 75%-ile"
#> 
#> $iqr
#> iqr 
#>  NA 
#> 
#> $range
#> min max 
#>  NA  NA 
#> 
#> $min
#> min 
#>  NA 
#> 
#> $max
#> max 
#>  NA 
#> 
#> $median_range
#> median    min    max 
#>     NA     NA     NA 
#> attr(,"label")
#> [1] "Median (Min - Max)"
#> 
#> $cv
#> cv 
#> NA 
#> 
#> $geom_mean
#> geom_mean 
#>       NaN 
#> 
#> $geom_mean_ci
#> mean_ci_lwr mean_ci_upr 
#>          NA          NA 
#> attr(,"label")
#> [1] "Geometric Mean 95% CI"
#> 
#> $geom_cv
#> geom_cv 
#>      NA 
#> 

## Management of NA values.
x <- c(NA_real_, 1)
s_summary(x, na.rm = TRUE)
#> $n
#> n 
#> 1 
#> 
#> $sum
#> sum 
#>   1 
#> 
#> $mean
#> mean 
#>    1 
#> 
#> $sd
#> sd 
#> NA 
#> 
#> $se
#> se 
#> NA 
#> 
#> $mean_sd
#> mean   sd 
#>    1   NA 
#> 
#> $mean_se
#> mean   se 
#>    1   NA 
#> 
#> $mean_ci
#> mean_ci_lwr mean_ci_upr 
#>          NA          NA 
#> attr(,"label")
#> [1] "Mean 95% CI"
#> 
#> $mean_sei
#> mean_sei_lwr mean_sei_upr 
#>           NA           NA 
#> attr(,"label")
#> [1] "Mean -/+ 1xSE"
#> 
#> $mean_sdi
#> mean_sdi_lwr mean_sdi_upr 
#>           NA           NA 
#> attr(,"label")
#> [1] "Mean -/+ 1xSD"
#> 
#> $mean_pval
#> p_value 
#>      NA 
#> attr(,"label")
#> [1] "Mean p-value (H0: mean = 0)"
#> 
#> $median
#> median 
#>      1 
#> 
#> $mad
#> mad 
#>   0 
#> 
#> $median_ci
#> median_ci_lwr median_ci_upr 
#>            NA            NA 
#> attr(,"conf_level")
#> [1] NA
#> attr(,"label")
#> [1] "Median 95% CI"
#> 
#> $quantiles
#> quantile_0.25 quantile_0.75 
#>             1             1 
#> attr(,"label")
#> [1] "25% and 75%-ile"
#> 
#> $iqr
#> iqr 
#>   0 
#> 
#> $range
#> min max 
#>   1   1 
#> 
#> $min
#> min 
#>   1 
#> 
#> $max
#> max 
#>   1 
#> 
#> $median_range
#> median    min    max 
#>      1      1      1 
#> attr(,"label")
#> [1] "Median (Min - Max)"
#> 
#> $cv
#> cv 
#> NA 
#> 
#> $geom_mean
#> geom_mean 
#>         1 
#> 
#> $geom_mean_ci
#> mean_ci_lwr mean_ci_upr 
#>          NA          NA 
#> attr(,"label")
#> [1] "Geometric Mean 95% CI"
#> 
#> $geom_cv
#> geom_cv 
#>      NA 
#> 
s_summary(x, na.rm = FALSE)
#> $n
#> n 
#> 2 
#> 
#> $sum
#> sum 
#>  NA 
#> 
#> $mean
#> mean 
#>   NA 
#> 
#> $sd
#> sd 
#> NA 
#> 
#> $se
#> se 
#> NA 
#> 
#> $mean_sd
#> mean   sd 
#>   NA   NA 
#> 
#> $mean_se
#> mean   se 
#>   NA   NA 
#> 
#> $mean_ci
#> mean_ci_lwr mean_ci_upr 
#>          NA          NA 
#> attr(,"label")
#> [1] "Mean 95% CI"
#> 
#> $mean_sei
#> mean_sei_lwr mean_sei_upr 
#>           NA           NA 
#> attr(,"label")
#> [1] "Mean -/+ 1xSE"
#> 
#> $mean_sdi
#> mean_sdi_lwr mean_sdi_upr 
#>           NA           NA 
#> attr(,"label")
#> [1] "Mean -/+ 1xSD"
#> 
#> $mean_pval
#> p_value 
#>      NA 
#> attr(,"label")
#> [1] "Mean p-value (H0: mean = 0)"
#> 
#> $median
#> median 
#>     NA 
#> 
#> $mad
#> mad 
#>  NA 
#> 
#> $median_ci
#> median_ci_lwr median_ci_upr 
#>            NA            NA 
#> attr(,"conf_level")
#> [1] NA
#> attr(,"label")
#> [1] "Median 95% CI"
#> 
#> $quantiles
#> quantile_0.25 quantile_0.75 
#>            NA            NA 
#> attr(,"label")
#> [1] "25% and 75%-ile"
#> 
#> $iqr
#> iqr 
#>  NA 
#> 
#> $range
#> min max 
#>  NA  NA 
#> 
#> $min
#> min 
#>  NA 
#> 
#> $max
#> max 
#>  NA 
#> 
#> $median_range
#> median    min    max 
#>     NA     NA     NA 
#> attr(,"label")
#> [1] "Median (Min - Max)"
#> 
#> $cv
#> cv 
#> NA 
#> 
#> $geom_mean
#> geom_mean 
#>        NA 
#> 
#> $geom_mean_ci
#> mean_ci_lwr mean_ci_upr 
#>          NA          NA 
#> attr(,"label")
#> [1] "Geometric Mean 95% CI"
#> 
#> $geom_cv
#> geom_cv 
#>      NA 
#> 

x <- c(NA_real_, 1, 2)
s_summary(x, stats = NULL)
#> $n
#> n 
#> 2 
#> 
#> $sum
#> sum 
#>   3 
#> 
#> $mean
#> mean 
#>  1.5 
#> 
#> $sd
#>        sd 
#> 0.7071068 
#> 
#> $se
#>  se 
#> 0.5 
#> 
#> $mean_sd
#>      mean        sd 
#> 1.5000000 0.7071068 
#> 
#> $mean_se
#> mean   se 
#>  1.5  0.5 
#> 
#> $mean_ci
#> mean_ci_lwr mean_ci_upr 
#>   -4.853102    7.853102 
#> attr(,"label")
#> [1] "Mean 95% CI"
#> 
#> $mean_sei
#> mean_sei_lwr mean_sei_upr 
#>            1            2 
#> attr(,"label")
#> [1] "Mean -/+ 1xSE"
#> 
#> $mean_sdi
#> mean_sdi_lwr mean_sdi_upr 
#>    0.7928932    2.2071068 
#> attr(,"label")
#> [1] "Mean -/+ 1xSD"
#> 
#> $mean_pval
#>   p_value 
#> 0.2048328 
#> attr(,"label")
#> [1] "Mean p-value (H0: mean = 0)"
#> 
#> $median
#> median 
#>    1.5 
#> 
#> $mad
#> mad 
#>   0 
#> 
#> $median_ci
#> median_ci_lwr median_ci_upr 
#>            NA            NA 
#> attr(,"conf_level")
#> [1] NA
#> attr(,"label")
#> [1] "Median 95% CI"
#> 
#> $quantiles
#> quantile_0.25 quantile_0.75 
#>             1             2 
#> attr(,"label")
#> [1] "25% and 75%-ile"
#> 
#> $iqr
#> iqr 
#>   1 
#> 
#> $range
#> min max 
#>   1   2 
#> 
#> $min
#> min 
#>   1 
#> 
#> $max
#> max 
#>   2 
#> 
#> $median_range
#> median    min    max 
#>    1.5    1.0    2.0 
#> attr(,"label")
#> [1] "Median (Min - Max)"
#> 
#> $cv
#>       cv 
#> 47.14045 
#> 
#> $geom_mean
#> geom_mean 
#>  1.414214 
#> 
#> $geom_mean_ci
#>  mean_ci_lwr  mean_ci_upr 
#>   0.01729978 115.60839614 
#> attr(,"label")
#> [1] "Geometric Mean 95% CI"
#> 
#> $geom_cv
#>  geom_cv 
#> 52.10922 
#> 

## Benefits in `rtables` contructions:
require(rtables)
dta_test <- data.frame(
  Group = rep(LETTERS[1:3], each = 2),
  sub_group = rep(letters[1:2], each = 3),
  x = 1:6
)

## The summary obtained in with `rtables`:
basic_table() %>%
  split_cols_by(var = "Group") %>%
  split_rows_by(var = "sub_group") %>%
  analyze(vars = "x", afun = s_summary) %>%
  build_table(df = dta_test)
#> Warning: number of items to replace is not a multiple of replacement length
#> Warning: number of items to replace is not a multiple of replacement length
#> Warning: number of items to replace is not a multiple of replacement length
#> Warning: number of items to replace is not a multiple of replacement length
#> Warning: number of items to replace is not a multiple of replacement length
#> Warning: number of items to replace is not a multiple of replacement length
#> Warning: number of items to replace is not a multiple of replacement length
#> Warning: number of items to replace is not a multiple of replacement length
#> Warning: number of items to replace is not a multiple of replacement length
#> Warning: number of items to replace is not a multiple of replacement length
#> Warning: number of items to replace is not a multiple of replacement length
#> Warning: number of items to replace is not a multiple of replacement length
#>                                                  A                        B                       C                  
#> —————————————————————————————————————————————————————————————————————————————————————————————————————————————————————
#> a                                                                                                                    
#>   n                                              2                        1                       0                  
#>   sum                                            3                        3                       NA                 
#>   mean                                          1.5                       3                       NA                 
#>   sd                                     0.707106781186548               NA                       NA                 
#>   se                                            0.5                      NA                       NA                 
#>   mean_sd                              1.5, 0.707106781186548           3, NA                     NA                 
#>   mean_se                                     1.5, 0.5                  3, NA                     NA                 
#>   Mean 95% CI                   -4.85310236808735, 7.85310236808735      NA                       NA                 
#>   Mean -/+ 1xSE                                 1, 2                     NA                       NA                 
#>   Mean -/+ 1xSD                 0.792893218813452, 2.20710678118655      NA                       NA                 
#>   Mean p-value (H0: mean = 0)            0.204832764699133               NA                       NA                 
#>   median                                        1.5                       3                       NA                 
#>   mad                                            0                        0                       NA                 
#>   Median 95% CI                                  NA                      NA                       NA                 
#>   25% and 75%-ile                               1, 2                    3, 3                      NA                 
#>   iqr                                            1                        0                       NA                 
#>   range                                         1, 2                    3, 3                      NA                 
#>   min                                            1                        3                       NA                 
#>   max                                            2                        3                       NA                 
#>   Median (Min - Max)                         1.5, 1, 2                 3, 3, 3                    NA                 
#>   cv                                      47.1404520791032               NA                       NA                 
#>   geom_mean                               1.41421356237309                3                       NA                 
#>   Geometric Mean 95% CI         0.0172997815631007, 115.608396135236     NA                       NA                 
#>   geom_cv                                 52.1092246837487               NA                       NA                 
#> b                                                                                                                    
#>   n                                              0                        1                       2                  
#>   sum                                            NA                       4                       11                 
#>   mean                                           NA                       4                      5.5                 
#>   sd                                             NA                      NA               0.707106781186548          
#>   se                                             NA                      NA                      0.5                 
#>   mean_sd                                        NA                     4, NA           5.5, 0.707106781186548       
#>   mean_se                                        NA                     4, NA                  5.5, 0.5              
#>   Mean 95% CI                                    NA                      NA      -0.853102368087347, 11.8531023680873
#>   Mean -/+ 1xSE                                  NA                      NA                      5, 6                
#>   Mean -/+ 1xSD                                  NA                      NA       4.79289321881345, 6.20710678118655 
#>   Mean p-value (H0: mean = 0)                    NA                      NA               0.0577158767526089         
#>   median                                         NA                       4                      5.5                 
#>   mad                                            NA                       0                       0                  
#>   Median 95% CI                                  NA                      NA                       NA                 
#>   25% and 75%-ile                                NA                     4, 4                     5, 6                
#>   iqr                                            NA                       0                       1                  
#>   range                                          NA                     4, 4                     5, 6                
#>   min                                            NA                       4                       5                  
#>   max                                            NA                       4                       6                  
#>   Median (Min - Max)                             NA                    4, 4, 4                5.5, 5, 6              
#>   cv                                             NA                      NA                12.8564869306645          
#>   geom_mean                                      NA                       4                5.47722557505166          
#>   Geometric Mean 95% CI                          NA                      NA       1.71994304449266, 17.4424380482025 
#>   geom_cv                                        NA                      NA                12.945835316564           

## By comparison with `lapply`:
X <- split(dta_test, f = with(dta_test, interaction(Group, sub_group)))
lapply(X, function(x) s_summary(x$x))
#> $A.a
#> $A.a$n
#> n 
#> 2 
#> 
#> $A.a$sum
#> sum 
#>   3 
#> 
#> $A.a$mean
#> mean 
#>  1.5 
#> 
#> $A.a$sd
#>        sd 
#> 0.7071068 
#> 
#> $A.a$se
#>  se 
#> 0.5 
#> 
#> $A.a$mean_sd
#>      mean        sd 
#> 1.5000000 0.7071068 
#> 
#> $A.a$mean_se
#> mean   se 
#>  1.5  0.5 
#> 
#> $A.a$mean_ci
#> mean_ci_lwr mean_ci_upr 
#>   -4.853102    7.853102 
#> attr(,"label")
#> [1] "Mean 95% CI"
#> 
#> $A.a$mean_sei
#> mean_sei_lwr mean_sei_upr 
#>            1            2 
#> attr(,"label")
#> [1] "Mean -/+ 1xSE"
#> 
#> $A.a$mean_sdi
#> mean_sdi_lwr mean_sdi_upr 
#>    0.7928932    2.2071068 
#> attr(,"label")
#> [1] "Mean -/+ 1xSD"
#> 
#> $A.a$mean_pval
#>   p_value 
#> 0.2048328 
#> attr(,"label")
#> [1] "Mean p-value (H0: mean = 0)"
#> 
#> $A.a$median
#> median 
#>    1.5 
#> 
#> $A.a$mad
#> mad 
#>   0 
#> 
#> $A.a$median_ci
#> median_ci_lwr median_ci_upr 
#>            NA            NA 
#> attr(,"conf_level")
#> [1] NA
#> attr(,"label")
#> [1] "Median 95% CI"
#> 
#> $A.a$quantiles
#> quantile_0.25 quantile_0.75 
#>             1             2 
#> attr(,"label")
#> [1] "25% and 75%-ile"
#> 
#> $A.a$iqr
#> iqr 
#>   1 
#> 
#> $A.a$range
#> min max 
#>   1   2 
#> 
#> $A.a$min
#> min 
#>   1 
#> 
#> $A.a$max
#> max 
#>   2 
#> 
#> $A.a$median_range
#> median    min    max 
#>    1.5    1.0    2.0 
#> attr(,"label")
#> [1] "Median (Min - Max)"
#> 
#> $A.a$cv
#>       cv 
#> 47.14045 
#> 
#> $A.a$geom_mean
#> geom_mean 
#>  1.414214 
#> 
#> $A.a$geom_mean_ci
#>  mean_ci_lwr  mean_ci_upr 
#>   0.01729978 115.60839614 
#> attr(,"label")
#> [1] "Geometric Mean 95% CI"
#> 
#> $A.a$geom_cv
#>  geom_cv 
#> 52.10922 
#> 
#> 
#> $B.a
#> $B.a$n
#> n 
#> 1 
#> 
#> $B.a$sum
#> sum 
#>   3 
#> 
#> $B.a$mean
#> mean 
#>    3 
#> 
#> $B.a$sd
#> sd 
#> NA 
#> 
#> $B.a$se
#> se 
#> NA 
#> 
#> $B.a$mean_sd
#> mean   sd 
#>    3   NA 
#> 
#> $B.a$mean_se
#> mean   se 
#>    3   NA 
#> 
#> $B.a$mean_ci
#> mean_ci_lwr mean_ci_upr 
#>          NA          NA 
#> attr(,"label")
#> [1] "Mean 95% CI"
#> 
#> $B.a$mean_sei
#> mean_sei_lwr mean_sei_upr 
#>           NA           NA 
#> attr(,"label")
#> [1] "Mean -/+ 1xSE"
#> 
#> $B.a$mean_sdi
#> mean_sdi_lwr mean_sdi_upr 
#>           NA           NA 
#> attr(,"label")
#> [1] "Mean -/+ 1xSD"
#> 
#> $B.a$mean_pval
#> p_value 
#>      NA 
#> attr(,"label")
#> [1] "Mean p-value (H0: mean = 0)"
#> 
#> $B.a$median
#> median 
#>      3 
#> 
#> $B.a$mad
#> mad 
#>   0 
#> 
#> $B.a$median_ci
#> median_ci_lwr median_ci_upr 
#>            NA            NA 
#> attr(,"conf_level")
#> [1] NA
#> attr(,"label")
#> [1] "Median 95% CI"
#> 
#> $B.a$quantiles
#> quantile_0.25 quantile_0.75 
#>             3             3 
#> attr(,"label")
#> [1] "25% and 75%-ile"
#> 
#> $B.a$iqr
#> iqr 
#>   0 
#> 
#> $B.a$range
#> min max 
#>   3   3 
#> 
#> $B.a$min
#> min 
#>   3 
#> 
#> $B.a$max
#> max 
#>   3 
#> 
#> $B.a$median_range
#> median    min    max 
#>      3      3      3 
#> attr(,"label")
#> [1] "Median (Min - Max)"
#> 
#> $B.a$cv
#> cv 
#> NA 
#> 
#> $B.a$geom_mean
#> geom_mean 
#>         3 
#> 
#> $B.a$geom_mean_ci
#> mean_ci_lwr mean_ci_upr 
#>          NA          NA 
#> attr(,"label")
#> [1] "Geometric Mean 95% CI"
#> 
#> $B.a$geom_cv
#> geom_cv 
#>      NA 
#> 
#> 
#> $C.a
#> $C.a$n
#> n 
#> 0 
#> 
#> $C.a$sum
#> sum 
#>  NA 
#> 
#> $C.a$mean
#> mean 
#>   NA 
#> 
#> $C.a$sd
#> sd 
#> NA 
#> 
#> $C.a$se
#> se 
#> NA 
#> 
#> $C.a$mean_sd
#> mean   sd 
#>   NA   NA 
#> 
#> $C.a$mean_se
#> mean   se 
#>   NA   NA 
#> 
#> $C.a$mean_ci
#> mean_ci_lwr mean_ci_upr 
#>          NA          NA 
#> attr(,"label")
#> [1] "Mean 95% CI"
#> 
#> $C.a$mean_sei
#> mean_sei_lwr mean_sei_upr 
#>           NA           NA 
#> attr(,"label")
#> [1] "Mean -/+ 1xSE"
#> 
#> $C.a$mean_sdi
#> mean_sdi_lwr mean_sdi_upr 
#>           NA           NA 
#> attr(,"label")
#> [1] "Mean -/+ 1xSD"
#> 
#> $C.a$mean_pval
#> p_value 
#>      NA 
#> attr(,"label")
#> [1] "Mean p-value (H0: mean = 0)"
#> 
#> $C.a$median
#> median 
#>     NA 
#> 
#> $C.a$mad
#> mad 
#>  NA 
#> 
#> $C.a$median_ci
#> median_ci_lwr median_ci_upr 
#>            NA            NA 
#> attr(,"conf_level")
#> [1] NA
#> attr(,"label")
#> [1] "Median 95% CI"
#> 
#> $C.a$quantiles
#> quantile_0.25 quantile_0.75 
#>            NA            NA 
#> attr(,"label")
#> [1] "25% and 75%-ile"
#> 
#> $C.a$iqr
#> iqr 
#>  NA 
#> 
#> $C.a$range
#> min max 
#>  NA  NA 
#> 
#> $C.a$min
#> min 
#>  NA 
#> 
#> $C.a$max
#> max 
#>  NA 
#> 
#> $C.a$median_range
#> median    min    max 
#>     NA     NA     NA 
#> attr(,"label")
#> [1] "Median (Min - Max)"
#> 
#> $C.a$cv
#> cv 
#> NA 
#> 
#> $C.a$geom_mean
#> geom_mean 
#>       NaN 
#> 
#> $C.a$geom_mean_ci
#> mean_ci_lwr mean_ci_upr 
#>          NA          NA 
#> attr(,"label")
#> [1] "Geometric Mean 95% CI"
#> 
#> $C.a$geom_cv
#> geom_cv 
#>      NA 
#> 
#> 
#> $A.b
#> $A.b$n
#> n 
#> 0 
#> 
#> $A.b$sum
#> sum 
#>  NA 
#> 
#> $A.b$mean
#> mean 
#>   NA 
#> 
#> $A.b$sd
#> sd 
#> NA 
#> 
#> $A.b$se
#> se 
#> NA 
#> 
#> $A.b$mean_sd
#> mean   sd 
#>   NA   NA 
#> 
#> $A.b$mean_se
#> mean   se 
#>   NA   NA 
#> 
#> $A.b$mean_ci
#> mean_ci_lwr mean_ci_upr 
#>          NA          NA 
#> attr(,"label")
#> [1] "Mean 95% CI"
#> 
#> $A.b$mean_sei
#> mean_sei_lwr mean_sei_upr 
#>           NA           NA 
#> attr(,"label")
#> [1] "Mean -/+ 1xSE"
#> 
#> $A.b$mean_sdi
#> mean_sdi_lwr mean_sdi_upr 
#>           NA           NA 
#> attr(,"label")
#> [1] "Mean -/+ 1xSD"
#> 
#> $A.b$mean_pval
#> p_value 
#>      NA 
#> attr(,"label")
#> [1] "Mean p-value (H0: mean = 0)"
#> 
#> $A.b$median
#> median 
#>     NA 
#> 
#> $A.b$mad
#> mad 
#>  NA 
#> 
#> $A.b$median_ci
#> median_ci_lwr median_ci_upr 
#>            NA            NA 
#> attr(,"conf_level")
#> [1] NA
#> attr(,"label")
#> [1] "Median 95% CI"
#> 
#> $A.b$quantiles
#> quantile_0.25 quantile_0.75 
#>            NA            NA 
#> attr(,"label")
#> [1] "25% and 75%-ile"
#> 
#> $A.b$iqr
#> iqr 
#>  NA 
#> 
#> $A.b$range
#> min max 
#>  NA  NA 
#> 
#> $A.b$min
#> min 
#>  NA 
#> 
#> $A.b$max
#> max 
#>  NA 
#> 
#> $A.b$median_range
#> median    min    max 
#>     NA     NA     NA 
#> attr(,"label")
#> [1] "Median (Min - Max)"
#> 
#> $A.b$cv
#> cv 
#> NA 
#> 
#> $A.b$geom_mean
#> geom_mean 
#>       NaN 
#> 
#> $A.b$geom_mean_ci
#> mean_ci_lwr mean_ci_upr 
#>          NA          NA 
#> attr(,"label")
#> [1] "Geometric Mean 95% CI"
#> 
#> $A.b$geom_cv
#> geom_cv 
#>      NA 
#> 
#> 
#> $B.b
#> $B.b$n
#> n 
#> 1 
#> 
#> $B.b$sum
#> sum 
#>   4 
#> 
#> $B.b$mean
#> mean 
#>    4 
#> 
#> $B.b$sd
#> sd 
#> NA 
#> 
#> $B.b$se
#> se 
#> NA 
#> 
#> $B.b$mean_sd
#> mean   sd 
#>    4   NA 
#> 
#> $B.b$mean_se
#> mean   se 
#>    4   NA 
#> 
#> $B.b$mean_ci
#> mean_ci_lwr mean_ci_upr 
#>          NA          NA 
#> attr(,"label")
#> [1] "Mean 95% CI"
#> 
#> $B.b$mean_sei
#> mean_sei_lwr mean_sei_upr 
#>           NA           NA 
#> attr(,"label")
#> [1] "Mean -/+ 1xSE"
#> 
#> $B.b$mean_sdi
#> mean_sdi_lwr mean_sdi_upr 
#>           NA           NA 
#> attr(,"label")
#> [1] "Mean -/+ 1xSD"
#> 
#> $B.b$mean_pval
#> p_value 
#>      NA 
#> attr(,"label")
#> [1] "Mean p-value (H0: mean = 0)"
#> 
#> $B.b$median
#> median 
#>      4 
#> 
#> $B.b$mad
#> mad 
#>   0 
#> 
#> $B.b$median_ci
#> median_ci_lwr median_ci_upr 
#>            NA            NA 
#> attr(,"conf_level")
#> [1] NA
#> attr(,"label")
#> [1] "Median 95% CI"
#> 
#> $B.b$quantiles
#> quantile_0.25 quantile_0.75 
#>             4             4 
#> attr(,"label")
#> [1] "25% and 75%-ile"
#> 
#> $B.b$iqr
#> iqr 
#>   0 
#> 
#> $B.b$range
#> min max 
#>   4   4 
#> 
#> $B.b$min
#> min 
#>   4 
#> 
#> $B.b$max
#> max 
#>   4 
#> 
#> $B.b$median_range
#> median    min    max 
#>      4      4      4 
#> attr(,"label")
#> [1] "Median (Min - Max)"
#> 
#> $B.b$cv
#> cv 
#> NA 
#> 
#> $B.b$geom_mean
#> geom_mean 
#>         4 
#> 
#> $B.b$geom_mean_ci
#> mean_ci_lwr mean_ci_upr 
#>          NA          NA 
#> attr(,"label")
#> [1] "Geometric Mean 95% CI"
#> 
#> $B.b$geom_cv
#> geom_cv 
#>      NA 
#> 
#> 
#> $C.b
#> $C.b$n
#> n 
#> 2 
#> 
#> $C.b$sum
#> sum 
#>  11 
#> 
#> $C.b$mean
#> mean 
#>  5.5 
#> 
#> $C.b$sd
#>        sd 
#> 0.7071068 
#> 
#> $C.b$se
#>  se 
#> 0.5 
#> 
#> $C.b$mean_sd
#>      mean        sd 
#> 5.5000000 0.7071068 
#> 
#> $C.b$mean_se
#> mean   se 
#>  5.5  0.5 
#> 
#> $C.b$mean_ci
#> mean_ci_lwr mean_ci_upr 
#>  -0.8531024  11.8531024 
#> attr(,"label")
#> [1] "Mean 95% CI"
#> 
#> $C.b$mean_sei
#> mean_sei_lwr mean_sei_upr 
#>            5            6 
#> attr(,"label")
#> [1] "Mean -/+ 1xSE"
#> 
#> $C.b$mean_sdi
#> mean_sdi_lwr mean_sdi_upr 
#>     4.792893     6.207107 
#> attr(,"label")
#> [1] "Mean -/+ 1xSD"
#> 
#> $C.b$mean_pval
#>    p_value 
#> 0.05771588 
#> attr(,"label")
#> [1] "Mean p-value (H0: mean = 0)"
#> 
#> $C.b$median
#> median 
#>    5.5 
#> 
#> $C.b$mad
#> mad 
#>   0 
#> 
#> $C.b$median_ci
#> median_ci_lwr median_ci_upr 
#>            NA            NA 
#> attr(,"conf_level")
#> [1] NA
#> attr(,"label")
#> [1] "Median 95% CI"
#> 
#> $C.b$quantiles
#> quantile_0.25 quantile_0.75 
#>             5             6 
#> attr(,"label")
#> [1] "25% and 75%-ile"
#> 
#> $C.b$iqr
#> iqr 
#>   1 
#> 
#> $C.b$range
#> min max 
#>   5   6 
#> 
#> $C.b$min
#> min 
#>   5 
#> 
#> $C.b$max
#> max 
#>   6 
#> 
#> $C.b$median_range
#> median    min    max 
#>    5.5    5.0    6.0 
#> attr(,"label")
#> [1] "Median (Min - Max)"
#> 
#> $C.b$cv
#>       cv 
#> 12.85649 
#> 
#> $C.b$geom_mean
#> geom_mean 
#>  5.477226 
#> 
#> $C.b$geom_mean_ci
#> mean_ci_lwr mean_ci_upr 
#>    1.719943   17.442438 
#> attr(,"label")
#> [1] "Geometric Mean 95% CI"
#> 
#> $C.b$geom_cv
#>  geom_cv 
#> 12.94584 
#> 
#> 

# `s_summary.factor`

## Basic usage:
s_summary(factor(c("a", "a", "b", "c", "a")))
#> $n
#> [1] 5
#> 
#> $count
#> $count$a
#> [1] 3
#> 
#> $count$b
#> [1] 1
#> 
#> $count$c
#> [1] 1
#> 
#> 
#> $count_fraction
#> $count_fraction$a
#> [1] 3.0 0.6
#> 
#> $count_fraction$b
#> [1] 1.0 0.2
#> 
#> $count_fraction$c
#> [1] 1.0 0.2
#> 
#> 
#> $n_blq
#> [1] 0
#> 
# Empty factor returns NA-filled items.
s_summary(factor(levels = c("a", "b", "c")))
#> $n
#> [1] 0
#> 
#> $count
#> $count$a
#> [1] 0
#> 
#> $count$b
#> [1] 0
#> 
#> $count$c
#> [1] 0
#> 
#> 
#> $count_fraction
#> $count_fraction$a
#> [1] 0 0
#> 
#> $count_fraction$b
#> [1] 0 0
#> 
#> $count_fraction$c
#> [1] 0 0
#> 
#> 
#> $n_blq
#> [1] 0
#> 

## Management of NA values.
x <- factor(c(NA, "Female"))
x <- explicit_na(x)
s_summary(x, na.rm = TRUE)
#> $n
#> [1] 1
#> 
#> $count
#> $count$Female
#> [1] 1
#> 
#> 
#> $count_fraction
#> $count_fraction$Female
#> [1] 1 1
#> 
#> 
#> $n_blq
#> [1] 0
#> 
s_summary(x, na.rm = FALSE)
#> $n
#> [1] 2
#> 
#> $count
#> $count$Female
#> [1] 1
#> 
#> $count$`<Missing>`
#> [1] 1
#> 
#> 
#> $count_fraction
#> $count_fraction$Female
#> [1] 1.0 0.5
#> 
#> $count_fraction$`<Missing>`
#> [1] 1.0 0.5
#> 
#> 
#> $n_blq
#> [1] 0
#> 

## Different denominators.
x <- factor(c("a", "a", "b", "c", "a"))
s_summary(x, denom = "N_row", .N_row = 10L)
#> $n
#> [1] 5
#> 
#> $count
#> $count$a
#> [1] 3
#> 
#> $count$b
#> [1] 1
#> 
#> $count$c
#> [1] 1
#> 
#> 
#> $count_fraction
#> $count_fraction$a
#> [1] 3.0 0.3
#> 
#> $count_fraction$b
#> [1] 1.0 0.1
#> 
#> $count_fraction$c
#> [1] 1.0 0.1
#> 
#> 
#> $n_blq
#> [1] 0
#> 
s_summary(x, denom = "N_col", .N_col = 20L)
#> $n
#> [1] 5
#> 
#> $count
#> $count$a
#> [1] 3
#> 
#> $count$b
#> [1] 1
#> 
#> $count$c
#> [1] 1
#> 
#> 
#> $count_fraction
#> $count_fraction$a
#> [1] 3.00 0.15
#> 
#> $count_fraction$b
#> [1] 1.00 0.05
#> 
#> $count_fraction$c
#> [1] 1.00 0.05
#> 
#> 
#> $n_blq
#> [1] 0
#> 

# `s_summary.character`

## Basic usage:
s_summary(c("a", "a", "b", "c", "a"), .var = "x", verbose = FALSE)
#> $n
#> [1] 5
#> 
#> $count
#> $count$a
#> [1] 3
#> 
#> $count$b
#> [1] 1
#> 
#> $count$c
#> [1] 1
#> 
#> 
#> $count_fraction
#> $count_fraction$a
#> [1] 3.0 0.6
#> 
#> $count_fraction$b
#> [1] 1.0 0.2
#> 
#> $count_fraction$c
#> [1] 1.0 0.2
#> 
#> 
#> $n_blq
#> [1] 0
#> 
s_summary(c("a", "a", "b", "c", "a", ""), .var = "x", na.rm = FALSE, verbose = FALSE)
#> $n
#> [1] 6
#> 
#> $count
#> $count$a
#> [1] 3
#> 
#> $count$b
#> [1] 1
#> 
#> $count$c
#> [1] 1
#> 
#> $count$`NA`
#> [1] 1
#> 
#> 
#> $count_fraction
#> $count_fraction$a
#> [1] 3.0 0.5
#> 
#> $count_fraction$b
#> [1] 1.0000000 0.1666667
#> 
#> $count_fraction$c
#> [1] 1.0000000 0.1666667
#> 
#> $count_fraction$`NA`
#> [1] 1.0000000 0.1666667
#> 
#> 
#> $n_blq
#> [1] 0
#> 

# `s_summary.logical`

## Basic usage:
s_summary(c(TRUE, FALSE, TRUE, TRUE))
#> $n
#> [1] 4
#> 
#> $count
#> [1] 3
#> 
#> $count_fraction
#> [1] 3.00 0.75
#> 
#> $n_blq
#> [1] 0
#> 

## Management of NA values.
x <- c(NA, TRUE, FALSE)
s_summary(x, na.rm = TRUE)
#> $n
#> [1] 2
#> 
#> $count
#> [1] 1
#> 
#> $count_fraction
#> [1] 1.0 0.5
#> 
#> $n_blq
#> [1] 0
#> 
s_summary(x, na.rm = FALSE)
#> $n
#> [1] 3
#> 
#> $count
#> [1] 1
#> 
#> $count_fraction
#> [1] 1.0000000 0.3333333
#> 
#> $n_blq
#> [1] 0
#> 

## Different denominators.
x <- c(TRUE, FALSE, TRUE, TRUE)
s_summary(x, denom = "N_row", .N_row = 10L)
#> $n
#> [1] 4
#> 
#> $count
#> [1] 3
#> 
#> $count_fraction
#> [1] 3.0 0.3
#> 
#> $n_blq
#> [1] 0
#> 
s_summary(x, denom = "N_col", .N_col = 20L)
#> $n
#> [1] 4
#> 
#> $count
#> [1] 3
#> 
#> $count_fraction
#> [1] 3.00 0.15
#> 
#> $n_blq
#> [1] 0
#> 

# `a_summary.numeric`
a_summary(rnorm(10), .N_col = 10, .N_row = 20, .var = "bla")
#> RowsVerticalSection (in_rows) object print method:
#> ----------------------------
#>        row_name   formatted_cell indent_mod                   row_label
#> 1             n               10          0                           n
#> 2           sum              1.1          0                         Sum
#> 3          mean              0.1          0                        Mean
#> 4            sd              1.0          0                          SD
#> 5            se              0.3          0                          SE
#> 6       mean_sd        0.1 (1.0)          0                   Mean (SD)
#> 7       mean_se        0.1 (0.3)          0                   Mean (SE)
#> 8       mean_ci    (-0.63, 0.86)          0                 Mean 95% CI
#> 9      mean_sei    (-0.22, 0.44)          0               Mean -/+ 1xSE
#> 10     mean_sdi    (-0.93, 1.16)          0               Mean -/+ 1xSD
#> 11    mean_pval             0.74          0 Mean p-value (H0: mean = 0)
#> 12       median              0.2          0                      Median
#> 13          mad              0.0          0   Median Absolute Deviation
#> 14    median_ci    (-0.62, 1.12)          0               Median 95% CI
#> 15    quantiles       -0.3 - 0.7          0             25% and 75%-ile
#> 16          iqr              1.0          0                         IQR
#> 17        range       -2.2 - 1.5          0                   Min - Max
#> 18          min             -2.2          0                     Minimum
#> 19          max              1.5          0                     Maximum
#> 20 median_range 0.2 (-2.2 - 1.5)          0          Median (Min - Max)
#> 21           cv            918.5          0                      CV (%)
#> 22    geom_mean               NA          0              Geometric Mean
#> 23 geom_mean_ci               NA          0       Geometric Mean 95% CI
#> 24      geom_cv               NA          0         CV % Geometric Mean

# `a_summary.factor`
# We need to ungroup `count` and `count_fraction` first so that the rtables formatting
# functions can be applied correctly.
afun <- make_afun(
  getS3method("a_summary", "factor"),
  .ungroup_stats = c("count", "count_fraction")
)
afun(factor(c("a", "a", "b", "c", "a")), .N_row = 10, .N_col = 10)
#> RowsVerticalSection (in_rows) object print method:
#> ----------------------------
#>   row_name formatted_cell indent_mod row_label
#> 1        n              5          0         n
#> 2        a              3          0         a
#> 3        b              1          0         b
#> 4        c              1          0         c
#> 5        a        3 (60%)          0         a
#> 6        b        1 (20%)          0         b
#> 7        c        1 (20%)          0         c
#> 8    n_blq              0          0     n_blq

# `a_summary.character`
afun <- make_afun(
  getS3method("a_summary", "character"),
  .ungroup_stats = c("count", "count_fraction")
)
afun(c("A", "B", "A", "C"), .var = "x", .N_col = 10, .N_row = 10, verbose = FALSE)
#> RowsVerticalSection (in_rows) object print method:
#> ----------------------------
#>   row_name formatted_cell indent_mod row_label
#> 1        n              4          0         n
#> 2        A              2          0         A
#> 3        B              1          0         B
#> 4        C              1          0         C
#> 5        A        2 (50%)          0         A
#> 6        B        1 (25%)          0         B
#> 7        C        1 (25%)          0         C
#> 8    n_blq              0          0     n_blq

# `a_summary.logical`
afun <- make_afun(
  getS3method("a_summary", "logical")
)
afun(c(TRUE, FALSE, FALSE, TRUE, TRUE), .N_row = 10, .N_col = 10)
#> RowsVerticalSection (in_rows) object print method:
#> ----------------------------
#>         row_name formatted_cell indent_mod      row_label
#> 1              n              5          0              n
#> 2          count              3          0          count
#> 3 count_fraction        3 (60%)          0 count_fraction
#> 4          n_blq              0          0          n_blq

## Fabricated dataset.
dta_test <- data.frame(
  USUBJID = rep(1:6, each = 3),
  PARAMCD = rep("lab", 6 * 3),
  AVISIT  = rep(paste0("V", 1:3), 6),
  ARM     = rep(LETTERS[1:3], rep(6, 3)),
  AVAL    = c(9:1, rep(NA, 9))
)

# `summarize_vars()` in `rtables` pipelines
## Default output within a `rtables` pipeline.
l <- basic_table() %>%
  split_cols_by(var = "ARM") %>%
  split_rows_by(var = "AVISIT") %>%
  summarize_vars(vars = "AVAL")

build_table(l, df = dta_test)
#>                   A           B       C 
#> ————————————————————————————————————————
#> V1                                      
#>   n               2           1       0 
#>   Mean (SD)   7.5 (2.1)   3.0 (NA)    NA
#>   Median         7.5         3.0      NA
#>   Min - Max   6.0 - 9.0   3.0 - 3.0   NA
#> V2                                      
#>   n               2           1       0 
#>   Mean (SD)   6.5 (2.1)   2.0 (NA)    NA
#>   Median         6.5         2.0      NA
#>   Min - Max   5.0 - 8.0   2.0 - 2.0   NA
#> V3                                      
#>   n               2           1       0 
#>   Mean (SD)   5.5 (2.1)   1.0 (NA)    NA
#>   Median         5.5         1.0      NA
#>   Min - Max   4.0 - 7.0   1.0 - 1.0   NA

## Select and format statistics output.
l <- basic_table() %>%
  split_cols_by(var = "ARM") %>%
  split_rows_by(var = "AVISIT") %>%
  summarize_vars(
    vars = "AVAL",
    .stats = c("n", "mean_sd", "quantiles"),
    .formats = c("mean_sd" = "xx.x, xx.x"),
    .labels = c(n = "n", mean_sd = "Mean, SD", quantiles = c("Q1 - Q3"))
  )

results <- build_table(l, df = dta_test)
as_html(results)
#> <div class="rtables-all-parts-block rtables-container">
#>   <table class="table table-condensed table-hover">
#>     <tr>
#>       <th style="white-space:pre;"></th>
#>       <th class="text-center">A</th>
#>       <th class="text-center">B</th>
#>       <th class="text-center">C</th>
#>     </tr>
#>     <tr>
#>       <td class="text-left">V1</td>
#>       <td class="text-center"></td>
#>       <td class="text-center"></td>
#>       <td class="text-center"></td>
#>     </tr>
#>     <tr>
#>       <td class="text-left" style="padding-left: 3ch">n</td>
#>       <td class="text-center">2</td>
#>       <td class="text-center">1</td>
#>       <td class="text-center">0</td>
#>     </tr>
#>     <tr>
#>       <td class="text-left" style="padding-left: 3ch">Mean, SD</td>
#>       <td class="text-center">7.5, 2.1</td>
#>       <td class="text-center">3.0, NA</td>
#>       <td class="text-center">NA</td>
#>     </tr>
#>     <tr>
#>       <td class="text-left" style="padding-left: 3ch">Q1 - Q3</td>
#>       <td class="text-center">6.0 - 9.0</td>
#>       <td class="text-center">3.0 - 3.0</td>
#>       <td class="text-center">NA</td>
#>     </tr>
#>     <tr>
#>       <td class="text-left">V2</td>
#>       <td class="text-center"></td>
#>       <td class="text-center"></td>
#>       <td class="text-center"></td>
#>     </tr>
#>     <tr>
#>       <td class="text-left" style="padding-left: 3ch">n</td>
#>       <td class="text-center">2</td>
#>       <td class="text-center">1</td>
#>       <td class="text-center">0</td>
#>     </tr>
#>     <tr>
#>       <td class="text-left" style="padding-left: 3ch">Mean, SD</td>
#>       <td class="text-center">6.5, 2.1</td>
#>       <td class="text-center">2.0, NA</td>
#>       <td class="text-center">NA</td>
#>     </tr>
#>     <tr>
#>       <td class="text-left" style="padding-left: 3ch">Q1 - Q3</td>
#>       <td class="text-center">5.0 - 8.0</td>
#>       <td class="text-center">2.0 - 2.0</td>
#>       <td class="text-center">NA</td>
#>     </tr>
#>     <tr>
#>       <td class="text-left">V3</td>
#>       <td class="text-center"></td>
#>       <td class="text-center"></td>
#>       <td class="text-center"></td>
#>     </tr>
#>     <tr>
#>       <td class="text-left" style="padding-left: 3ch">n</td>
#>       <td class="text-center">2</td>
#>       <td class="text-center">1</td>
#>       <td class="text-center">0</td>
#>     </tr>
#>     <tr>
#>       <td class="text-left" style="padding-left: 3ch">Mean, SD</td>
#>       <td class="text-center">5.5, 2.1</td>
#>       <td class="text-center">1.0, NA</td>
#>       <td class="text-center">NA</td>
#>     </tr>
#>     <tr>
#>       <td class="text-left" style="padding-left: 3ch">Q1 - Q3</td>
#>       <td class="text-center">4.0 - 7.0</td>
#>       <td class="text-center">1.0 - 1.0</td>
#>       <td class="text-center">NA</td>
#>     </tr>
#>     <caption style="caption-side:top;"><div class="rtables-titles-block rtables-container">
#>         <div class="rtables-main-titles-block rtables-container">
#>           <p class="rtables-main-title"></p>
#>         </div>
#>         <div class="rtables-subtitles-block rtables-container"></div>
#>       </div>
#>     </caption>
#>   </table>
#>   <div class="rtables-footers-block rtables-container"></div>
#> </div>

## Use arguments interpreted by `s_summary`.
l <- basic_table() %>%
  split_cols_by(var = "ARM") %>%
  split_rows_by(var = "AVISIT") %>%
  summarize_vars(vars = "AVAL", na.rm = FALSE)

results <- build_table(l, df = dta_test)

## Handle `NA` levels first when summarizing factors.
dta_test$AVISIT <- NA_character_
dta_test <- df_explicit_na(dta_test)
l <- basic_table() %>%
  split_cols_by(var = "ARM") %>%
  summarize_vars(vars = "AVISIT", na.rm = FALSE)

results <- build_table(l, df = dta_test)
# \donttest{
Viewer(results)
# }